After a close 1st quarter Madison outscored Crest 28-9 in the 2nd quarter to put the game out of reach.
Madison Coach Brett Dannels was glad they overcame the sluggish start.
Ryan Wolgram scored a game-high 31 points to lead Madison.
Madison plays Lebo in the semi-finals.
Area Sub-state scores:
Burlingame 55 Cair Paravel 54 - vs Olpe (at Madison)
Hartford 48 Chase 30 - vs Elyria Christian (at Peabody)
Southern Coffey County 46 Marais des Cygnes Valley 42 - vs Altoona Midway (at St. Paul)
Waverly will play Chetopa in the semi-finals at St. Paul.