Kansas State outscored Kansas 47-27 to win the Sunflower Showdown for the 14th consecutive meeting Saturday.
Kansas State Coach Chris Klieman said they made enough plays.
Kansas State quarterback Will Howard threw 2 touchdown passes, one each to Phillip Brooks and Sammy Wheeler.
Deuce Vaughn and D.J. Giddens scored a rushing touchdown. Malik Knowles scored 2 rushing touchdowns.
Kansas was led by running back Devin Neal who scored two rushing touchdowns. Jalon Daniels and Terry Locklin each scored a rushing touchdown for Kansas.
Kansas Coach Lance Leipold said there were some positives from the game.
Kansas State will play TCU in the Big 12 Championship game next Saturday.
Kansas awaits their bowl bid.